Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep1320 | Late Breaking | ECE2024

in vitro study of 17-beta-estradiol effects on a renal cancer cell line

Rossi Lucrezia , Rosaria Ambrosio Maria , Chiara Zatelli Maria

Introduction: Renal carcinomas (RCs) are the most common kidney cancers, and their prognosis is affected by many factors; 5-year survival rate is >90% in patients with small tumors confined to the kidney. RC makes up 2-3% of cancers in adults aged between 50 and 70 years; in particular, the incidence in men is higher than women, 66.7 vs 33.3% of the cases, respectively. Aim: RC incidence is twice as high in men as in women. This difference could sugg...

ea0090p664 | Endocrine-related Cancer | ECE2023

Mutational profiles of typical and atypical bronchial carcinoids

Gagliardi Irene , Borges de Souza Patricia , Rossi Lucrezia , Rosaria Ambrosio Maria , Chiara Zatelli Maria

Introduction: Typical and Atypical bronchial carcinoids (TBC and ABC) are rare neuroendocrine neoplasms (NEN). TBC are low grade and well-differentiated NEN often with indolent clinical behavior, slow growth, rare extra-thoracic metastases, and with a long survival following surgical resection. Conversely, ABC have often a worse prognosis with a greater tendency to metastasize and recur. A better understanding of TBC and ABC genetic background would help in evaluating prognosi...

ea0063gp87 | Thyroid Nodules and Cancer | ECE2019

Intronic RAS and PI3KCA mutations identified by Next Generation Sequencing in thyroid nodules with indeterminate cytology may associate with follicular thyroid cancer

Borges de Souza Patricia , Rossi Lucrezia , Crociara Anna , Rossi Roberta , Ambrosio Maria Rosaria , Rossi Martina , Bondanelli Marta , Lanza Giovanni , Zatelli Maria Chiara

Introduction: Accurately discern malignant from benign nodules sometimes represents a real challenge. Fine needle aspiration (FNA) biopsy, ultrasound and The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) allow for accurate diagnosis in 60–80% of all nodules. However, 10–20% of thyroid FNAs yield an indeterminate cytology (BSRTC III and IV categories). The real malignancy rate of BSRTC III category is difficult to ascertain because histopathological anal...